Systematic identification of mammalian regulatory motifs' target genes and functions

Jason B. Warner1,6, Anthony A. Philippakis1,3,4,6, Savina A. Jaeger1,6, Fangxue Sherry He1,7, Jolinta Lin1,5, and Martha L. Bulyk1,2,3,4

1Division of Genetics, Department of Medicine; 2Department of Pathology; 3Harvard/MIT Division of Health Sciences and Technology (HST); Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.

4Harvard University Graduate Biophysics Program, Harvard Medical School, Boston, MA 02115.

5Department of Biology, MIT, Cambridge, MA 02139.

6These authors contributed equally to this work.

7Current address: The Institute for Genomic Research, Rockville, MD 20850.


Correspondence should be addressed to M.L.B. (




Supplementary Files:


Supplementary Text and Figures (PDF 7M)



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Click here to get PhylCRM software package (PhylCRM_preprocess and PhylCRM)


Click here to get Lever software package (PhylCRM_preprocess, Lever and Lever Statistics)

Questions, comments or suggestions regarding the materials presented here should be directed to Martha Bulyk (

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